Liposome siRNA Encapsulation (LSE) is a liposome assembly technique to enhance siRNA cargo loading into PEGylated neutral liposomes for improved biocompatibility and pharmacokinetics.  This results in liposomal nanocarriers with efficient nucleic acid encapsulation and enhanced cellular association, while minimizing the cytotoxic effects associated with cationic-mediated transfection. LSE is a quick, easy, reproducible, scalable method for nanoparticle-mediated applied transfection.

 

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