PICCBOXX is a tamper-evident device that minimizes unauthorized access to a central line and shows unambiguous evidence of tampering.

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Three kit sizes are available

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Demonstration Video


The risks of central line complications are especially high in endocarditis patients who use intravenous drugs (IVD). These patients are more likely to manipulate the central line, which may result in a central line-associated bloodstream infection (CLABSI). Claims associated with these infections may not be reimbursed by insurance companies, encumbering the hospital with the costs. Furthermore, such patients cannot be safely discharged to outpatient care or to a skilled nursing facility, which leaves the hospital unable to free up beds.


PICCBOXX a tamper-evident device that also minimizes unauthorized access to the central line. The device has a specially designed contoured enclosure that covers the lumen interface points in the central line and shows unambiguous evidence of having been opened by either a nurse or a patient. The value of the device has been demonstrated in high-risk patients recovering from endocarditis at two hospitals. These studies showed very promising results: the nurses surveyed stated that the device would not only demonstrate real evidence of inappropriate access to the central line but would also provide deterrence of inappropriate access to the central line. The nurses also stated that the device is easy to use and does not impair their workflow. Moreover, the CDC rule states that if there is documentation of tampering in the patient’s record, the resulting CLABSI does not count against the facility.

According to a nurse from one of the hospitals, “If people utilize this device and tampering is detected, that is basically all the documentation needed.”

This device will potentially enable hospitals to discharge patients who use IVD to outpatient care for further antibiotic treatment knowing that the IV line will not be used.


  • Provides unambiguous evidence of unauthorized PICC line access
  • Potentially enables intravenous drug users to be safely discharged for outpatient follow-on care
  • Minimal impact on nurse workflow
  • Easy to use

PICC, CLABSI, drug users, IVD, substance abuse, tamper, tamper evident, PICC tamper

Additional information


Small kit (10 boxes, 80 pins, 2 keys), Medium kit (20 boxes, 160 pins, 4 keys), Large kit (40 boxes, 300 pins, 5 keys)